Edzion Trial Paper Biology 2021

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100 marks/ 3 hours

Question 1.

Which of the following substances is incorrectly matched to how it is carried in mammalian blood?

SubstanceForm it is carried in the body
a) Nitrogenous wasteUrea mainly dissolved in blood plasma
b)Glucose Mainly dissolved in blood plasma
c) Carbon Dioxide Mainly dissolved in blood plasma
d)Oxygen Mainly dissolved in blood plasma

Question 2.

Which of the following immune system responses is characteristic of the adaptive immune system and correctly matched

Defence AdaptationFeature
a) InflammationSwelling to dilute the antigen and make it easier to access
b)PhagocytosisThe engulfing of the antigen by phagocytes
c) Killer T cells The killing of the antigen by killer T cells
d)Macrophagous Destruction and digestion of pathogens

Question 3.

Which of the following describes the daughter cells produced through meiosis

  • A. Two genetically different cells
  • B. Two genetically identical cells
  • C. Four genetically different cells
  • D. Four genetically identical cells

Question 4.

The scientist who discovered the inheritance patterns through careful breeding of snow peas was

  • A. Mendel
  • B. Darwin
  • C. Tatum
  • D. Watson

Question 5.

An organism suspected of causing a disease is described as being unicellular, having a
nucleus and lacking a cell wall.
How is this organism classified?

  • A. A bacterium
  • B. A fungus
  • C. A protozoan
  • D. A virus

Question 6.

A recombinant technology was applied to cotton, this formed BT cotton, which of the following is not a concern of this

  • a) Unfair socioeconomic benefit to richer farmers
  • b) The BT cotton escaping into the wild
  • c) The pests which feed on the cotton going extinct
  • d) The fact scientists may be ‘playing God’

Question 7.

What is the inheritance patter of the below pedigree

File:Wiki Drawing - Autosomal Recessive (2).svg - Wikimedia Commons
  • a) Autosomal Recessive
  • b) Sex-linked Recessive
  • c) Autosomal Dominant
  • d) Sex-linked Dominant

Question 8.

How do B cells help with the immune response

  • A. They mass produce specific antibodies.
  • B. They stimulate the cloning of specific T cells.
  • C. They are cloned and differentiate to become specific cytotoxic T cells.
  • D. They produce cytokines that stimulate the cloning of specific phagocytes

Question 9.

Which of the following will not limit the incidence of malaria

  • a) taking anti-malarial drugs
  • b) spraying swamps with insecticides
  • c) using mosquito nets over beds
  • d) administering a malaria vaccine

Question 10.

The mother is a carrier for colour blindness, an sex-linked recessive trait, if the father is not colour blind, what is the probability their first child will be colour blind?

  • a) 100%
  • b) 75%
  • c) 50%
  • d) 25%

Question 11.

An advantage of asexual reproduction over sexual reproduction is

  • a) Better parenting of the offspring
  • b) Faster reproduction times
  • c) Greater genetic diversity
  • d) Longer lifespan of offspring

Question 12.

In microbiology, a negative control

  • a) Makes an experiment valid
  • b) Allows you to see if there are contaminants not caused by inoculation
  • c) Are not required
  • d) Means you are only changing the independent variable to determine the effect on the dependent variable

Question 13.

A mutation resulted in the codon, AAU, to change to, AAC, this is an example of where the U was swapped with a C

DNA and RNA codon tables - Wikipedia
  • a) A frame shift mutation
  • b) A missense mutation
  • c) A silent mutation
  • d) An addition mutation

Question 14.

The phenotype of an organism is

  • a) The same the entire life of the organism
  • b) Dependent only on the genotype
  • c) Always the same as the parents phenotype
  • d) The physical expression of the genotype of a living organism

Question 15.

An example of asexual reproduction used in agriculture is

  • a) Cross pollination
  • b) Genetically engineered seeds
  • c) Plants can’t produce asexually
  • d) Tissue culture

Question 16.

Which of the following will increase the decrease the prevalence of a disease in a population

  • a) Matching the incidence with the recovery and mortality rate
  • b) Increasing the mortality rate
  • c) Decreasing the recovery rate
  • d) Increasing the incidence rate

Question 17.

Koch’s postulates have a short fall, they could not work for:

  • a) Bacterial Infections
  • b) Any Infection, these only apply to non-infectious diseases
  • c) Prion Infections
  • D) Fungal Infections

Question 18.

What is a difference between DNA and RNA

  • a) DNA carries genetic information, RNA is folded into proteins
  • b) DNA is less stable then RNA
  • c) DNA contains thiamine, RNA contains Uracil
  • d) DNA and RNA are some molecule, two RNAs make one DNA

Question 19.

Select the correct statement regarding the process of mitosis

  • a) Mitosis results in an increase in genetic diversity for a cell through crossing over before before homologous chromosomes are separated
  • b) Mitosis only has one round of prophase, metaphase, anaphase, telophase in order to form two identical daughter cells
  • c) Mitosis allows a diploid cell to form four haploid cells.
  • d) Mitosis means all cells are capable of asexual reproduction

Question 20.

DNA profiling allows for

  • a) The base pair sequence of DNA to be known
  • b) Differentiation of individuals based on their genotypes
  • c) The exact time of death for a patient to be determined
  • d) DNA profilin is a future technology which will be widely used for crime scene analysis

Question 21.

Compare and contrast internal fertilisation and external fertilisation [6 marks]

Question 22.

i) Evaluate Pasteur’s contribution to our modern understanding of infectious diseases. [6 marks]

ii) Evaluate Koch’s contribution to our modern understanding of infectious diseases. [6 marks]

Question 23.

Evaluate the use of genetic engineering to combat malaria. [8 marks]

Question 24.

i. Outline the procedure you used to model Pasteur’s experiment [4 marks]

ii. Explain how you could increase accuracy of Pasteur swan neck flask model [2 mark]

iii. Evaluate the significance of models for communication of scientific concepts, using an example. [6 marks]

Question 25.

Evaluate whether transgenic species should be used for agricultural purposes, using examples in your answer. [6 marks]

Question 26.

A new disease has started to infect cows at a farm.

  1. Explain how you could determine whether the disease is infectious for humans [3 marks]
  2. Explain a protocol that could be used to limit the spread, if the disease is found to be pathogenic. [3 marks]

Question 27.

Outline procedures which could be used to limit the spread of an infectious disease of your choosing [4 marks]

Question 28.

i. Using examples, compare and contrast positive and negative feedback loops. [4 marks]

ii. Explain the importance of homeostasis, using a specific example to humans. [3 marks]

Question 29.

Evaluate the following statement [5 marks]

“Sexual reproduction is always better then asexual reproduction for the continuation of a species”

Question 30.

i. Outline a recombinant technology used in the pharmaceutical industry [2 marks]

ii. Outline how this technology works [4 marks]

iii. Evaluate the ethical implications of this technology [8 marks]


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  1. d) Mainly carried in red blood cells
  2. c) A, B and D are all characteristic of the innate immune response – lesson: Immune Response
  3. c) Meiosis VS Mitosis
  4. a)
  5. c) Figure 1.
  6. c) The pests were previously being killed by pesticide so this is not as much of a concern.
  7. a) The genetics of inheritance patterns
  8. a) Immune Response
  9. a) Reduces prevalence, not incidence
  10. d) The genetics of inheritance patterns
  11. b)
  12. b)
  13. c)
  14. d) Best answer, dependent on environment and genotype
  15. d)
  16. b)
  17. c)
  18. c) Molecular Biology’s Central Dogma
  19. b)
  20. d)
Protozoan infection - Wikipedia
Figure 1. A plasmodium, a nucleus and no cell wall

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